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Filtered Search Results
Medchemexpress LLC 1-Naphthalenecarboxaldehyde, 2-hydroxy-, S-(4-methylphenyl)thiooxime | 906439-72-3 | 99.9% | 250 MG
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COH34 is a potent and specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with an IC50 of 0.37 nM. It binds to the catalytic domain of PARG, which prolongs PARylation at DNA lesions and traps DNA repair factors. This compound efficiently kills PARP inhibitor-resistant cancer cells and induces lethality in cancer cells with DNA repair defects, exhibiting antitumor activity in xenograft mouse cancer models. It is intended for research use only.
- Potent and specific PARG inhibitor with an IC50 of 0.37 nM
- Binds to the catalytic domain of PARG (Kd=0.547 μM)
- Efficiently kills PARP inhibitor-resistant cancer cells
- Induces lethality in cancer cells with DNA repair defects
- Exhibits antitumor activity in xenograft mouse cancer models
- For research use only
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Medchemexpress LLC N-Nitrosodibutylamine | 924-16-3 | 100.0% | 250 MG
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N-Nitrosodibutylamine is a nitrosamine found in drinking water. It regulates the caspase pathway, induces apoptosis, and causes hepatocarcinoma and oxidative DNA damage. It is for research use only.
- Regulates the caspase pathway
- Induces apoptosis
- Causes hepatocarcinoma and oxidative DNA damage
- For research use only
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eMolecules EMOLECULES INC
5000492812 PYRIMIDINE-5-CARBOXALDEHYD 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000281739 5-BROMOMETHYLTHALIDO 250MG
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![Medchemexpress LLC PAMAM dendrimer, ethylenediamine core, generation 3.0 | 153891-46-4 | 6908.84 g/mol | [NH2(CH2)2NH2]:(G=3); dendri PAMAM(NH2)32 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000201933.png-250.jpg)
Medchemexpress LLC PAMAM dendrimer, ethylenediamine core, generation 3.0 | 153891-46-4 | 6908.84 g/mol | [NH2(CH2)2NH2]:(G=3); dendri PAMAM(NH2)32 | 250 MG
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Polyamidoamine (PAMAM) is a generation-3 polyamidoamine dendrimer provided as a solution for formulation and drug-delivery research. It has internal encapsulation capability and a biocompatible surface suitable for nanoparticle and carrier studies.
- Used for drug delivery and encapsulation research.
- Provided as a 20% (w/w) solution in methanol for convenient handling.
- Liquid appearance, colorless to light yellow.
- Available in small research sizes for formulation development.
- Contains PAMAM dendrimer structure (G3.0) with amine termini suitable for functionalization.
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Medchemexpress LLC Thiamine-d3 (hydrochloride) | 2241872-28-4 | 340.29 | 1 MG
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Thiamine-d3 hydrochloride is the deuterium labeled Thiamine hydrochloride, an essential micronutrient that functions as a cofactor for many central metabolic enzymes. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during the drug development process. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Chemscene CHEMSCENE
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5000575840 4-AMINO-6-CHLOROPYRIMIDINE 25G
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Medchemexpress LLC Carbinoxamine maleate salt | 3505-38-2 | 98.78% | 250 MG
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Carbinoxamine maleate salt is a histamine H1 receptor antagonist available as a white to off-white solid. It has a high purity of 98.78% and a molecular formula of C20H23ClN2O5.
- Targets histamine H1 receptor
- 98.78% purity
- Molecular weight of 406.86
- White to off-white solid appearance
- Recommended storage at 4°C, sealed and away from moisture
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Medchemexpress LLC PHYTANIC ACID METHYL 50MG
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5000206602 PHYTANIC ACID METHYL 50MG
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Medchemexpress LLC 2-O-DMT-Sulfonyldiethanol phosphoramidite | 108783-02-4 | 97.0% | 656.77 | 250 MG
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2-O-DMT-Sulfonyldiethanol phosphoramidite is a chemical compound used in the synthesis of oligonucleotides. It functions as a phosphoramidite and is primarily for research purposes. This product supports studies related to DNA/RNA synthesis and cell cycle/DNA damage pathways.
- Phosphoramidite for oligonucleotide synthesis
- Suitable for DNA/RNA synthesis research
- Involved in cell cycle/DNA damage pathways
- For research use only
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eMolecules EMOLECULES INC
5000488388 ETHYL 2-OXOCYCLOHEXANECARBO 5G
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eMolecules EMOLECULES INC
5000488567 METHYL 2-CHLOROPYRIMIDINE-5 1G
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Medchemexpress LLC Trans-3-(3-pyridyl)acrylic acid | 19337-97-4 | MFCD00006410 | 99.9% | 149.2 g/mol | C8H7NO2 | 1 ML
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trans-3-(3-pyridyl)acrylic acid is a trans-3-aryl acrylic acid reported to inhibit tobacco mosaic virus (TMV). This listing is supplied as a 10 mM solution in DMSO (1 mL) for research use; the compound is reported at high purity and has documented storage recommendations for solvent and powder forms.
- Ready-to-use 10 mM solution in DMSO, supplied in a 1 mL vial.
- High reported purity suitable for screening and research applications.
- Reported antiviral activity against tobacco mosaic virus in the literature.
- Compact vial format reduces preparation time and solvent handling.
- Stable when stored under recommended conditions for solvent and powder forms.
- Includes safety and quality documentation such as SDS and COA.
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Chemscene CHEMSCENE
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5000576024 PYRIMIDINE-4 5-DIAMINE 10G
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Medchemexpress LLC 9-Aminononanoic acid 250mg
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9-Aminononanoic acid can be used as a PROTAC linker and other conjugation in the synthesis of PROTACs 9-Aminononanoic acid is an alkane chain with terminal carboxlic acid and amine groups The amino group (NH2) is reactive with carboxylic acids activated NHS esters carbonyls (ketone aldehyde) etc The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond
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